Alfeprol [Russian]
Brand names,
Alfeprol [Russian]
Analogs
Alfeprol [Russian]
Brand Names Mixture
Alfeprol [Russian]
Chemical_Formula
C15H23NO2
Alfeprol [Russian]
RX_link
No information avaliable
Alfeprol [Russian]
fda sheet
Alfeprol [Russian]
msds (material safety sheet)
Alfeprol [Russian]
Synthesis Reference
Brandstrom et al., Acta Pharm. Suecica 3, 303 (1966)
Alfeprol [Russian]
Molecular Weight
249.349 g/mol
Alfeprol [Russian]
Melting Point
107-109 oC
Alfeprol [Russian]
H2O Solubility
547 mg/L
Alfeprol [Russian]
State
Solid
Alfeprol [Russian]
LogP
3.144
Alfeprol [Russian]
Dosage Forms
Tablet
Alfeprol [Russian]
Indication
For the treatment of hypertension, angina, and arrhythmia
Alfeprol [Russian]
Pharmacology
Alprenolol is a non-selective beta-blocker used in the treatment of hypertension, edema, ventricular tachycardias, and atrial fibrillation. Alprenolol impairs AV node conduction and decreases sinus rate and may also increase plasma triglycerides and decrease HDL-cholesterol levels. Alprenolol is nonpolar and hydrophobic, with low to moderate lipid solubility. Alprenolol has little to no intrinsic sympathomimetic activity and, unlike some other beta-adrenergic blocking agents, alprenolol has little direct myocardial depressant activity and does not have an anesthetic-like membrane-stabilizing action.
Alfeprol [Russian]
Absorption
No information avaliable
Alfeprol [Russian]
side effects and Toxicity
LD50=597.0 mg/kg (Orally in rats)
Alfeprol [Russian]
Patient Information
No information avaliable
Alfeprol [Russian]
Organisms Affected
Humans and other mammals